Improved survival of patients with hypermutation in uterine serous carcinoma
نویسندگان
چکیده
•Uterine serous carcinoma (USC) is an aggressive subtype of endometrial cancer.•Mutations in DNA polymerase ε gene (POLE) are detected in a subset of USC and confer a strong mutator phenotype.•USC patients diagnosed with POLE mutations experience a significantly better prognosis.
منابع مشابه
طبقهبندی مجدد کارسینوماهای سروز تخمدان با روش جدید تقسیمبندی دوگانه (two-tier) و بررسی بروز ژن P53 با رنگآمیزی ایمونوهیستوشیمی
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